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Rheumatoid lung disease

Lung disease - rheumatoid arthritis; Rheumatoid nodules; Rheumatoid lung

 

Rheumatoid lung disease is a group of lung problems related to rheumatoid arthritis . The condition can include:

  • Blockage of the small airways (bronchiolitis obliterans)
  • Fluid in the chest ( pleural effusions )
  • High blood pressure in the lungs ( pulmonary hypertension )
  • Lumps in the lungs (nodules)
  • Scarring ( pulmonary fibrosis )

Causes

 

Lung problems are common in rheumatoid arthritis. They often cause no symptoms.

The cause of lung disease associated with rheumatoid arthritis is unknown. Sometimes, the medicines used to treat rheumatoid arthritis, especially methotrexate, may result in lung disease.

 

Symptoms

 

Symptoms may include any of the following:

  • Chest pain
  • Cough
  • Fever
  • Shortness of breath
  • Joint pain
  • Joint stiffness
  • Joint swelling
  • Skin nodules

 

Exams and Tests

 

The doctor may hear crackles (rales) when listening to the lungs with a stethoscope. Or, there may be decreased breath sounds, wheezing, a rubbing sound, or normal breath sounds.

The following tests may show signs of rheumatoid lung disease:

  • Chest x-ray
  • CT scan of the chest
  • Echocardiogram (may show pulmonary hypertension)
  • Lung biopsy (bronchoscopic, video-assisted, or open )
  • Lung function tests
  • Needle inserted into the fluid around the lung ( thoracentesis )
  • Blood tests for rheumatoid arthritis

 

Treatment

 

Many people with this condition have no symptoms. Treatment is aimed at the health problems causing the lung problem and the complications caused by the disorder. Corticosteroids or other medicines that suppress the immune system are sometimes useful.

 

Outlook (Prognosis)

 

Outcome is related to the underlying disorder and the type and severity of lung disease. In severe cases, lung transplantation can be considered.

 

Possible Complications

 

Rheumatoid lung disease may lead to:

  • Pneumothorax
  • Pulmonary hypertension

 

When to Contact a Medical Professional

 

Call your health care provider right away if you have rheumatoid arthritis and you develop unexplained breathing difficulties.

 

 

References

Corte TJ, duBois RM, Wells AU. Connective tissue diseases. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 65.

Lake F, Proudman S. Rheumatoid arthritis and lung disease: from mechanisms to a practical approach. Semin Respir Crit Care Med . 2014;35:222-238. PMID: 24668537 www.ncbi.nlm.nih.gov/pubmed/24668537 .

 
  • Bronchoscopy - illustration

    Bronchoscopy is a surgical technique for viewing the interior of the airways. Using sophisticated flexible fiber optic instruments, surgeons are able to explore the trachea, main stem bronchi, and some of the small bronchi. In children, this procedure may be used to remove foreign objects that have been inhaled. In adults, the procedure is most often used to take samples of (biopsy) suspicious lesions and for culturing specific areas in the lung.

    Bronchoscopy

    illustration

  • Respiratory system - illustration

    Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.

    Respiratory system

    illustration

    • Bronchoscopy - illustration

      Bronchoscopy is a surgical technique for viewing the interior of the airways. Using sophisticated flexible fiber optic instruments, surgeons are able to explore the trachea, main stem bronchi, and some of the small bronchi. In children, this procedure may be used to remove foreign objects that have been inhaled. In adults, the procedure is most often used to take samples of (biopsy) suspicious lesions and for culturing specific areas in the lung.

      Bronchoscopy

      illustration

    • Respiratory system - illustration

      Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.

      Respiratory system

      illustration

    A Closer Look

     

    Talking to your MD

     

      Self Care

       

        Tests for Rheumatoid lung disease

         

         

        Review Date: 6/22/2015

        Reviewed By: Denis Hadjiliadis, MD, MHS, Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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