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    Dermatomyositis

    Dermatomyositis is a muscle disease that involves inflammation and a skin rash. It is a type of inflammatory myopathy.

    Causes

    The cause of dermatomyositis is unknown. Experts think it may be due to a viral infection of the muscles or a problem with the body's immune system. It may also occur in patients who have cancer in the abdomen, lung, or other parts of the body.

    Anyone can develop dermatomyositis. It most commonly occurs in children age 5 - 15 and adults age 40 - 60. Women develop this condition more often than men.

    Polymyositis is a similar condition, but the symptoms do not include a skin rash.

    Symptoms

    • Problems swallowing
    • Muscle weakness, stiffness, or soreness
    • Purple color to the upper eyelids
    • Purple-red skin rash
    • Shortness of breath

    The muscle weakness may come on suddenly or develop slowly over weeks or months. You may have trouble raising your arms over your head, getting up from a sitting position, and climbing stairs.

    The rash may appear on your face, knuckles, neck, shoulders, upper chest, and back.

    Exams and Tests

    The doctor will do a physical exam. Tests may include:

    • Bloods test to check levels of creatine phosphokinase and aldolase
    • Blood tests for autoimmune diseases
    • ECG
    • Electromyography
    • Magnetic resonance imaging (MRI)
    • Muscle biopsy
    • Skin biopsy

    Treatment

    The disease is treated with anti-inflammatory medicines called corticosteroids and other drugs that suppress the immune system.

    When your muscles get stronger, your doctor may tell you to slowly cut back on your doses. Most people with this condition must take a medicine called prednisone for the rest of their lives.

    If a tumor is causing the condition, the muscle weakness and rash may get better when the tumor is removed.

    Outlook (Prognosis)

    Symptoms may go away completely in some people, such as children.

    The condition may be fatal in adults due to severe muscle weakness, malnutrition, pneumonia, or lung failure. The major causes of death with this condition are cancer and lung disease.

    Possible Complications

    • Acute renal failure
    • Cancer (malignancy)
    • Inflammation of the heart
    • Joint pain
    • Lung disease

    When to Contact a Medical Professional

    Call your health care provider if you have muscle weakness or other symptoms of this condition.

    References

    Jorizzo JL, Vleugels RA. In: Bolognia JL, Jorizzo JL, Schaffer JV, et al, eds. Dermatology. 3rd ed. Philadelphia, Pa: Mosby Elsevir; 2012:chap 42.

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      Tests for Dermatomyositis

        Review Date: 1/22/2013

        Reviewed By: Kevin Berman, MD, PhD, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.

        The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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