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    Hydrocephalus

    Water on the brain

    Hydrocephalus is a buildup of fluid inside the skull that leads to brain swelling.

    Hydrocephalus means "water on the brain."

    Causes

    Hydrocephalus is due to a problem with the flow ofthe fluid that surrounds the brain. This fluid is called the cerebrospinalfluid, or CSF. It surrounds the brain and spinal cord, and helps cushion the brain.

    CSF normally moves through the brain and the spinal cord, and is soakedinto the bloodstream.CSF levels in the brain can rise if:

    • The flow of CSF is blocked
    • It does not get absorbed into the blood properly
    • Your brain makes too much of it

    Too much CSFputs pressure on the brain. This pushes the brain upagainst the skull and damage brain tissue.

    Hydrocephalus may begin while the baby is growing in the womb. It is common in babies who have a myelomeningocele, a birth defect in which the spinal column does not close properly.

    Hydrocephalus may also be due to:

    • Genetic defects
    • Certain infections during pregnancy

    In young children, hydrocephalus may be due to:

    • Infections that affect the central nervous system (such as meningitis or encephalitis), especially in infants
    • Bleeding in the brain during or soon after delivery (especially in premature babies)
    • Injury before, during, or after childbirth, including subarachnoid hemorrhage
    • Tumors of the central nervous system, including the brain or spinal cord
    • Injury or trauma

    Hydrocephalus most often occurs in children. Another type, called normal pressure hydrocephalus, may occur in adults and the elderly.

    Symptoms

    Symptoms of hydrocephalus depend on:

    • Age
    • Amount of brain damage
    • What is causing the buildup of CSF fluid

    In infants with hydrocephalus, it causes the fontanelle (soft spot) to bulge and the head to be larger than expected. Early symptoms may also include:

    • Eyes that appear to gaze downward
    • Irritability
    • Seizures
    • Separated sutures
    • Sleepiness
    • Vomiting

    Symptoms that may occur in older children can include:

    • Brief, shrill, high-pitched cry
    • Changes in personality, memory, or the ability to reason or think
    • Changes in facial appearance and eye spacing
    • Crossed eyes or uncontrolled eye movements
    • Difficulty feeding
    • Excessive sleepiness
    • Headache
    • Irritability, poor temper control
    • Loss of bladder control (urinary incontinence)
    • Loss of coordination and trouble walking
    • Muscle spasticity (spasm)
    • Slow growth (child 0 - 5 years)
    • Slow or restricted movement
    • Vomiting

    Exams and Tests

    The doctor or nurse will examine the baby. This may show:

    • Stretched or swollen veins on the baby's scalp
    • Abnormal sounds when the health care provider taps lightly on the skull, suggesting a problem with the skull bones
    • All or part of the head may be larger than normal, usually in the front part
    • Eyes that look "sunken in"
    • White part of the eye appears over the colored area, making it look like a "setting sun"
    • Reflexes may be normal

    Head circumference measurements, repeated over time, may show that the head is getting bigger.

    A head CT scan is one of the best tests for identifying hydrocephalus. Other tests that may be done include:

    • Arteriography
    • Brain scan using radioisotopes
    • Cranial ultrasound (an ultrasound of the brain)
    • Lumbar puncture and examination of the cerebrospinal fluid (rarely done)
    • Skull x-rays

    Treatment

    The goal of treatment is to reduce or prevent brain damage by improving the flow of CSF.

    Surgery may be done to remove a blockage, if possible.

    If not,a flexible tube called a shuntmay be placed in the brain to re-route the flow of CSF. The shunt sends CSF to another part of the body, such as the belly area, where it can be absorbed.

    Other treatments may include:

    • Antibiotics are given if there are signs of infection. Severe infections may require the shunt to be removed.
    • A procedure called endoscopic third ventriculostomy (ETV), which relieves pressure without replacing the shunt.
    • Removing or burning away (cauterizing) the parts of the brain that produce CSF.

    The child will need regular check-ups to make sure there are no further problems. Testsare regularly done to check the child's developmental and for intellectual, neurological, or physical problems.

    Visiting nurses, social services, support groups, and local agencies can provide emotional support and assist with the care of a child with hydrocephalus who has significant brain damage.

    Outlook (Prognosis)

    Without treatment, up to 6 in 10 people with hydrocephalus will die. Those who survive have different amounts of intellectual, physical, and neurological disabilities.

    The outlook depends on the cause.Hydrocephalus that is not due to aninfection has the best outlook. Persons with hydrocephalus caused by tumors usually do very poorly.

    Most children with hydrocephalus that survive for 1 year will have a fairly normal life span.

    Possible Complications

    The shunt may become blocked. Symptoms of such a blockage include headache and vomiting. Surgeons may be able to help the shunt open without having to replace it.

    There may be other problems with the shunt, such as kinking, tube separation, or infection in the area of the shunt.

    Other complications may include:

    • Complications of surgery
    • Infections such as meningitis or encephalitis
    • Intellectual impairment
    • Nerve damage (decrease in movement, sensation, function)
    • Physical disabilities

    When to Contact a Medical Professional

    Seek immediate medical care if your child has any symptoms of this disorder. Go to the emergency room or call 911 if emergency symptoms occur, which include:

    • Breathing problems
    • Extreme drowsiness or sleepiness
    • Feeding difficulties
    • Fever
    • High-pitched cry
    • No pulse (heart beat)
    • Seizures
    • Severe headache
    • Stiff neck
    • Vomiting

    You should also call your health care provider if the child has been diagnosed with hydrocephalus and the condition gets worse and you are unable to care for him or her at home.

    Prevention

    Protect the head of an infant or child from injury. Prompt treatment of infections and other disorders associated with hydrocephalus may reduce the risk of developing the disorder.

    References

    Kinsman SL, Johnston MV. Hydrocephalus. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 585.11.

    Rosenberg GA. Brain edema and disorders of cerebrospinal fluid circulation. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J, eds. Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Butterworth-Heinemann; 2008:chap 63.

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    • Skull of a newborn

      illustration

      • Skull of a newborn

        illustration

      Self Care

        Tests for Hydrocephalus

          Review Date: 11/12/2012

          Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.

          The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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