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    Orbital pseudotumor

    Idiopathic orbital inflammatory syndrome (IOIS)

    Orbital pseudotumor is a swelling of the tissues behind the eye in an area called the orbit. The orbit is the bony cavity in the skull where the eye sits. It protects the eyeball and the muscles and tissue that surround it.

    Unlike cancerous tumors, orbital pseudotumor does not spread to other tissues or places in the body.

    Causes

    The cause is unknown. It most commonly affects young women, although it can still occur at any age.

    Symptoms

    • Pain in eye - may be severe
    • Restricted eye movement
    • Decreased vision
    • Double vision
    • Eye swelling (proptosos)
    • Red eye (rare)

    Exams and Tests

    Signs of pseudotumor can be seen when the eye is examined. Tests must be done to tell the difference between pseudotumor and a cancerous tumor and eye problems that can occur in people with thyroid disease.

    Tests may include:

    • CT scan of the head
    • MRI of the head
    • Ultrasound of the head
    • Skull x-ray
    • Biopsy

    Treatment

    Mild cases may go away without treatment. More severe cases will usually respond to treatment with corticosteroids. Very severe cases may develop damaging pressure on the eye, and require surgical movement of the bones of the orbit to relieve pressure on the eyeball.

    Outlook (Prognosis)

    Most cases are mild and do well. Severe cases may be resistant to treatment and visual loss may occur. Orbital pseudotumor usually involves only one eye.

    Possible Complications

    Severe cases of orbital pseudotumor may push the eye forward to the extent that the lids can no longer protect the cornea, leading to drying of the affected eye. This can lead to damage to the clarity of the cornea, or to corneal ulcer (wound). The eye muscles may not be able to properly aim the eye, and double vision may result.

    When to Contact a Medical Professional

    Patients with pseudotumor will be closely followed by an ophthalmologist with experience in the treatment of orbital disease.

    If you experience irritation of the cornea, redness, pain, or decreased vision, call your ophthalmologist or general health care provider right away.

    References

    Yanoff M, Cameron D. Diseases of the visual system. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 431.

    Karesh JW, On AV, Hirschbein MJ. Noninfectious orbital inflammatory disease. In: Tasman W, Jaeger EA, eds. Duane’s Ophthalmology. 15th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2009:chap 35.

    Glaser JS, Tse DT, Chang WJ. Orbital disease and neuro-ophthalmology. In: Tasman W, Jaeger EA, eds. Duane’s Ophthalmology. 15th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2009:chap 14.

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    • Skull anatomy

      illustration

      • Skull anatomy

        illustration

      Self Care

        Tests for Orbital pseudotumor

          Review Date: 9/3/2012

          Reviewed By: Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Franklin W. Lusby, MD, Ophthalmologist, Lusby Vision Institute, La Jolla, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.

          The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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