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    Glomus jugulare tumor

    Paraganglioma - glomus jugulare

    A glomus jugulare tumor is a tumor of a part of the temporal bone in the skull. This tumor can affect the ear, upper neck, base of the skull, and the surrounding blood vessels and nerves.

    Causes

    A glomus jugulare tumor grows in the temporal bone of the skull, in an area called the jugular foramen. The jugular foramen is also where the jugular vein and several important nerves exit the skull.

    This area contains nerve fibers, called glomus bodies, which normally respond to changes in body temperature or blood pressure.

    These tumors usually occur later in life, around age 60 or 70, but they can appear at any age. The cause of a glomus jugulare tumor is unknown. Usually, there are no known risk factors. Glomus tumors have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).

    Symptoms

    Symptoms may include:

    • Difficulty swallowing (dysphagia)
    • Dizziness
    • Hearing problems or loss
    • Hearing pulsations in the ear
    • Hoarseness
    • Pain
    • Weakness or loss of movement in the face (facial nerve palsy)

    Exams and Tests

    Glomus jugulare tumors are diagnosed by physical examination and imaging tests, including:

    • Cerebral angiography
    • CT scan
    • MRI scan

    Treatment

    Glomus jugulare tumors are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms. The main treatment is surgery. Surgery is complex and is usually done by both a neurosurgeon and a head and neck surgeon (neurotologist).

    In some cases, a procedure called embolization is performed before surgery to prevent the tumor from bleeding too much during surgery.

    After surgery, radiation therapy may be used to treat any part of the tumor that could not be removed completely.

    Some glomus tumors can be treated with stereotactic radiosurgery.

    Outlook (Prognosis)

    Patients who have surgery or radiation tend to do well. More than 90% of those with glomus jugulare tumors are cured.

    Possible Complications

    The most common complications are due to nerve damage, which may be caused by the tumor itself or damage during surgery. Nerve damage can lead to:

    • Change in voice
    • Difficulty swallowing
    • Hearing loss
    • Paralysis of the face

    When to Contact a Medical Professional

    Call your health care provider if you:

    • Are having difficulty with hearing or swallowing
    • Develop pulsations in your ear
    • Notice a lump in your neck
    • Notice any problems with the muscles in your face

    References

    Rucker JC. Cranial neuropathies. In: Bradley WG, Daroff RB, Fenichel GM, Jankovic J, eds. Neurology in Clinical Practice. 5th ed. Philadelphia, Pa: Butterworth-Heinemann; 2008:chap 74.

    Marsh M, Jenkins HA. Temporal bone neoplasms and lateralcranial base surgery. In: Flint PW, Haughey BH, Lund LJ, et al, eds. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2010:chap 176.

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          A Closer Look

            Tests for Glomus jugulare tumor

              Review Date: 3/14/2012

              Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Seth Schwartz, MD, MPH, Otolaryngologist, Virginia Mason Medical Center, Seattle, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.

              The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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