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    Periactin overdose

    Cyproheptadine hydrochloride overdose

    Periactin is an antihistamine, which is a drugused to relieve allergy symptoms. A periactin overdose occurs when someone takes too much of this drug.

    This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or the National Poison Control Center at 1-800-222-1222.

    Poisonous Ingredient

    Cyproheptadine

    Where Found

    The generic drug name for Periactin is cyproheptadine hydrochloride. This medicine may also be sold under the following brand names:

    • Klarivitina
    • Nuran
    • Periatinol

    This list may not be all-inclusive.

    Symptoms

    • Eyes and skin
      • Dilated pupils
      • Flushed skin
    • Heart and blood vessels
      • Convulsions
      • Low blood pressure
      • Rapid heartbeat
    • Nervous system
      • Agitation
      • Coma
      • Confusion
      • Delirium
      • Depression
      • Disorientation
      • Drowsiness
      • Excitation
      • Hallucinations
      • Nervousness
      • Unsteadiness

    Before Calling Emergency

    Determine the following information:

    • Patient's age, weight, and condition
    • Name of the product (ingredients and strengths, if known)
    • Time it was swallowed
    • Amount swallowed
    • If the medication was prescribed for the patient

    However, DO NOT delay calling for help if this information is not immediately available.

    Poison Control

    In the United States, call 1-800-222-1222 to speak with a local poison control center. This hotline number will let you talk to experts in poisoning. They will give you further instructions

    This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

    What to Expect at the Emergency Room

    The health care provider will measure and monitor the patient's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The patient may receive:

    • Activated charcoal
    • Gastric lavage
    • Laxative
    • Medicine (antidote) to reverse the effect of the poison

    Outlook (Prognosis)

    If the patient lives the first 24 hours, survival is likely. Few patients actually die from an antihistamine overdose.

    References

    Goldfrank LR, ed. Goldfrank's Toxicologic Emergencies. 8th ed. New York, NY: McGraw Hill; 2006.

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          Tests for Periactin overdose

            Review Date: 1/29/2013

            Reviewed By: Eric Perez, MD, St. Luke's / Roosevelt Hospital Center, NY, NY, and Pegasus Emergency Group (Meadowlands and Hunterdon Medical Centers), NJ. Review provided by VeriMed Healthcare Network. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.

            The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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            St. Luke's Hospital - 232 South Woods Mill Road - Chesterfield, MO 63017 Main Number: 314-434-1500 Emergency Dept: 314-205-6990 Patient Billing: 888-924-9200
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