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    Heterochromia

    Differently colored eyes; Eyes - different colors

    Heterochromia isdifferent colored eyes in the same person.

    Considerations

    Heterochromia isuncommon in humans, butquite common in dogs (such as Dalmatians and Australian sheep dogs), cats, and horses.

    Causes

    Most cases of heterochromia are hereditary, caused by a disease or syndrome, or due to an injury. Sometimes one eye may change color following certain diseases or injuries.

    Specific causes of eye color changes include:

    • Bleeding (hemorrhage)
    • Familial heterochromia
    • Foreign object in the eye
    • Glaucoma, or some medications used to treat it
    • Injury
    • Mild inflammation affecting only one eye
    • Neurofibromatosis
    • Waardenburg syndrome

    When to Contact a Medical Professional

    Consult your health care provider if you notice new changes in the color of one eye, or two differently colored eyes in your infant. A thorough eye examination is needed to be sure this isn't a symptom of a medical problem.

    Some conditions and syndromes associated with heterochromia, such as pigmentary glaucoma, can only be detected by a thorough eye exam.

    What to Expect at Your Office Visit

    Your health care provider may ask the following questions to help evaluate the cause:

    • Did you notice the two different eye colors when the child was born, shortly after the birth, or recently?
    • Are any other symptoms present?

    An infant with heterochromia should be examined by both a pediatrician and an ophthalmologist for other possible problems.

    A complete eye examination can rule out most causes of heterochromia. If there doesn't seem to be an underlying disorder, no further testing may be necessary. If another disorder is suspected, diagnostic tests, such as blood tests or chromosome studies, may be done to confirm the diagnosis.

    References

    Olitsky SE, Hug D, Plummer LS, Stass-Isern M. Abnormalities of pupil and iris. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 614.

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    • Heterochromia

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      • Heterochromia

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      Review Date: 11/7/2011

      Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

      The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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