CO2 blood testBicarbonate test; HCO3-; Carbon dioxide test; TCO2; Total CO2; CO2 test - serum
CO2 is carbon dioxide. This article discusses the laboratory test to measures the amount of carbon dioxide in the liquid part of your blood, called the serum.
In the body, most of the CO2 is in the form of a substance called bicarbonate (HCO3-). Therefore, the CO2 blood test is really a measure of your blood bicarbonate level.
A blood sample is needed. Most of the time blood is typically drawn from a vein located on the inside of the elbow or the back of the hand.
Many medicines can interfere with blood test results.
- Your health care provider will tell you if you need to stop taking any medicines before you have this test.
- Do not stop or change your medications without talking to your doctor first.
You may feel slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn.
The CO2 test is most often done as part of an electrolyte or basic metabolic panel. Changes in your CO2 level may suggest that you are losing or retaining fluid. This may cause an imbalance in your body's electrolytes.
CO2 levels in the blood are affected by kidney and lung function. The kidneys help maintain the normal bicarbonate levels.
The normal range is 23-29 mEq/L (milliequivalents per liter).
Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The example above shows the common measurement rangeof results for these tests. Some laboratories use different measurements or may test different specimens.
Abnormal levels may be due to the following problems:
- Addison disease
- Ethylene glycol poisoning
- Kidney disease
- Lactic acidosis
- Metabolic acidosis
- Methanol poisoning
- Salicylate toxicity (such as aspirin overdose)
The following conditions may also alter bicarbonate levels:
Seifter JL. Acid-base disorders. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 120.
Review Date: 4/29/2013
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.