If you take any of the following drugs, you should not use German chamomile without first talking to your health care provider:

Anticoagulants (blood-thinning medication) -- Chamomile may increase the risk of bleeding when taken with anticoagulant drugs such as warfarin.

Sedatives -- Chamomile can increase the effect of drugs that have a sedating effect, including:

• Anticonvulsants, such as phenytoin (Dilantin) and valproic acid (Depakote)
• Barbiturates
• Benzodiazepines, such as alprazolam (Xanax) and diazepam (Valium)
• Drugs to treat insomnia, such as zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Lunesta), and ramelteon (Rozerem)
• Tricyclic antidepressants, such as amitriptyline (Elavil)
• Alcohol

The same is true of herbs with a sedating effect, such as valerian, kava, and catnip.

Other drugs -- Because chamomile is broken down by certain liver enzymes, it may interact with other drugs that are broken down by the same enzymes. Those drugs may include:

• Fexofenadine (Seldane)
• Statins (drugs that can lower cholesterol)
• Birth control pills
• Some antifungal drugs