Drug treatment - NSAIDs
St. Luke's Hospital
Main Number: 314-434-1500 Emergency Dept: 314-205-6990 Patient Billing: 888-924-9200
Find a Physician Payment Options Locations & Directions
Follow us on: facebook twitter Mobile Email Page Email Page Print Page Print Page Increase Font Size Decrease Font Size Font Size
America's 50 Best Hospitals
Meet the Doctor
Spirit of Women
Community Health Needs Assessment
Home > Health Information

Senior's Center

Drug treatment - NSAIDs

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) are the most commonly used type of medication for back pain. They work by blocking a substance called prostaglandin. Normally, prostaglandins dilate blood vessels (leading to increased blood flow) and promote inflammation, both of which can contribute to pain. By stopping the usual actions of prostaglandins, NSAIDs help reduce pain and inflammation.

Types of NSAIDs

NSAIDs are available over-the-counter or by prescription. They are either seletive or non-selective. The prescription versions are generally stronger and last longer.

Non-selective NSAIDs include:

  • Aspirin
  • Diclofenac (Voltaren)
  • Etodolac (Lodine)
  • Ibuprofen (Advil, Motrin, Motrin IB, Nuprin)
  • Indomethacin (Indocin)
  • Ketoprofen (Orudis, Oruvail)
  • Nabumetone (Relafan)
  • Naproxen (Aleve, Anaprox, Naprosyn)
  • Piroxicam (Feldene)
  • Salsalate (Disalcid)
  • Sulindac (Clinoril)
  • Tolemetin (Tolectin)

Selective NSAIDs include:

Risk of ulcers and GI bleeding

Regular use of non-selective NSAIDs, especially long-term use, can have serious complications like ulcers, bleeding from your gastrointestinal (GI) tract, and kidney damage. (Selective COX-2 inhibitors, however, may be associated with a lower risk of ulcers and gastrointestinal bleeding.) You are at particular risk of developing ulcers from these drugs (including bleeding ulcers) if you:

  • Are over age 60
  • Have had an ulcer in the past or history of bleeding from your GI tract
  • Drink alcohol on a regular basis
  • Take certain medications, such as warfarin (Coumadin), steroids, or alendronate (Fosamax)

Other possible side effects

NSAIDs can cause or worsen the following conditions:

  • Cardiovascular: Evidence from large research trials has showed increased rates of fatal and non-fatal cardiovascular events and heart attacks in patients taking NSAIDs.
  • High blood pressure: NSAIDs can increase blood pressure. If you have high blood pressure, check with your doctor before using NSAIDs, especially if you take blood pressure lowering medication.
  • Kidney disease: NSAIDs can cause kidney damage. If you already have any type of kidney disease, don't use NSAIDs. If while taking an NSAID, you develop sudden weight gain or fluid retention (for example, you notice swelling in your legs), notify your doctor right away.
  • Diabetes: NSAIDs can cause a change in blood sugar. Check with your doctor before using NSAIDs if you have diabetes. You may still be able to use them, but you may need to follow your blood sugars closely and, with the help of your doctor, adjust your diabetes medications appropriately.

Finally, NSAIDs can cause:

  • Dizziness
  • Tinnitus (ringing in your ear)
  • Headache
  • Skin rash
  • Confusion

 


Review Date: 6/29/2011
Reviewed By: Andrew W. Piasecki, MD, Camden Bone and Joint, LLC, Orthopaedic Surgery/Sports Medicine, Camden, SC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com


Back  |  Top
About Us
Contact Us
History
Mission
Locations & Directions
Quality Reports
Annual Reports
Honors & Awards
Community Health Needs
Assessment

Newsroom
Services
Brain & Spine
Cancer
Heart
Maternity
Orthopedics
Pulmonary
Sleep Medicine
Urgent Care
Women's Services
All Services
Patients & Visitors
Locations & Directions
Find a Physician
Tour St. Luke's
Patient & Visitor Information
Contact Us
Payment Options
Financial Assistance
Send a Card
Mammogram Appointments
Health Tools
My Personal Health
mystlukes
Spirit of Women
Health Information & Tools
Clinical Trials
Health Risk Assessments
Employer Programs -
Passport to Wellness

Classes & Events
Classes & Events
Spirit of Women
Donate & Volunteer
Giving Opportunities
Volunteer
Physicians & Employees
For Physicians
Remote Access
Medical Residency Information
Pharmacy Residency Information
Physician CPOE Training
Careers
Careers
St. Luke's Hospital - 232 South Woods Mill Road - Chesterfield, MO 63017 Main Number: 314-434-1500 Emergency Dept: 314-205-6990 Patient Billing: 888-924-9200
Copyright © St. Luke's Hospital Website Terms and Conditions  |  Privacy Policy  |  Patient Notice of Privacy Policies PDF Sitemap St. Luke's Mobile