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What is Pulmonary Hypertension?
Pulmonary Hypertension (PAH) begins when tiny arteries in your lungs become narrow or blocked. This causes increased resistance to the flow of blood in the lungs, which in turn raises pressure within the blood vessels or what could be termed "high blood pressure of the lungs." As a result, the right side of the heart, which pumps blood into the lungs, has to pump against a higher resistance to blood flow. This makes it more difficult to pump the blood through the lungs, eventually causing the heart muscle to weaken and sometimes fail completely.
PAH Studies
COMPASS II is an ongoing trial for subjects with Pulmonary Hypertension who are currently on sidenafil (aka: Revatio or Viagra), where bosentan (aka: Tracleer, which works to relax smooth muscle, in turn, lowering pressure in the lungs and improving oxygen levels) is added therapy to sildenafil vs sildenafil alone.
If you are interested in any of the studies or more information, contact Sue or Anna at 314-439-LUNG (5864).
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