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Senior Staff

Ronald Leidenfrost, MD

Chairman - Heart and Vascular Institute
Ronald D. Leidenfrost, MD, is chairman of the Heart and Vascular Institute at St. Luke's Hospital. He joined St. Luke's in 1984 as division chief of cardiothoracic surgery and launched the hospital's heart surgery program. In St. Louis, St. Luke’s is the exclusive alliance provider for the nation’s No. 1 heart hospital, the Cleveland Clinic Heart, Vascular and Thoracic Institute.

Board-certified in internal medicine and thoracic and cardiac surgery, he specializes in adult cardiac surgery, valvular heart disease, coronary artery disease, on and off pump coronary artery by-pass surgery, mitral and aortic valve repair and replacement, surgery for thoracic aneurysm, cardiac reoperations, cardiac pacemakers and the Maze procedure for atrial fibrillation. No other hospital in the greater St. Louis area has performed more beating-heart (off pump) procedures. Dr. Leidenfrost is the principal investigator for IND 14,905, FDA Phase I Clinical Trial "Biologically Modified Saphenous Vein Transplants for improved CABG Outcomes" utilizing Nona-Arginine (9 polymer L-Arginine).

He earned his medical degree from State University of New York Upstate Medical School and completed an internship, residencies and fellowships at Barnes-Jewish Hospital and Boston Children's Hospital.