Meniscal allograft transplantation
Meniscal allograft transplantation is a type of surgery in which a meniscus -- a cartilage ring in the knee -- is placed into your knee. The new meniscus is taken from a person who has died (cadaver) and donated his or her tissue.
If your doctor finds that you are a good candidate for a meniscus transplant, x-rays of your knee are usually taken to find a meniscus that will fit your knee. The donated meniscus is tested in the lab for possible diseases.
Other surgeries, such as ligament or cartilage repairs, may be done at the time of the meniscus transplant or with a separate surgery.
The meniscus transplant is usually performed by knee arthroscopy. You will likely be asleep during the surgery. When arthroscopy is performed, a camera is inserted into your knee through a small hole, and is connected to a video monitor.
First, the surgeon will check the cartilage and ligaments of your knee. Then the surgeon will confirm that a meniscus transplant is appropriate, and that you don't have severe arthritis of the knee.
The new meniscus will be prepared to fit your knee correctly. If any tissue is left from your old meniscus, it will be removed using a shaver or other instruments. A surgical cut is made in the front of your knee to insert the new meniscus into the knee. Sutures are used to sew the new meniscus in place. Another cut may be needed to sew the meniscus in place. Screws or other devices may be used to hold the meniscus in place.
After the surgery is finished, the cuts are closed, and a dressing is placed over the wound. During arthroscopy, most surgeons take pictures of the procedure from the video monitor to show you what was found and what was done.
Why the Procedure Is Performed
There are two cartilage rings in the center of each knee, one on the inside (medial meniscus) and one on the outside (lateral meniscus). When a meniscus is torn, it is commonly removed by knee arthroscopy. However, some people can still have pain after the meniscus is removed, or several years after the meniscus is removed.
A meniscus transplant places a new meniscus in your knee where the meniscus is missing. This procedure is only done in cases of meniscus tears that are so severe that all or nearly all of the meniscus cartilage has to be removed. The new meniscus can help with knee pain and possibly prevent future arthritis. The new meniscus is tissue taken from a person who has died (allograft).
Meniscus allograft transplantation may be recommended for knee problems such as:
- Inability to play sports or other activities
- Knee pain
- Knee that gives way
- Unstable knee
The risks from any anesthesia are:
- Allergic reactions to medications
- Problems breathing
The risks for any surgery are:
- Nerve damage
Other risks include:
- Stiffness of the knee
- Failure of the surgery to relieve symptoms
- Failure of the meniscus to heal
- Tear of the new meniscus
- Disease from the transplanted meniscus
- Pain in the knee
- Weakness of the knee
After the Procedure
Meniscus allograft transplantation is a difficult surgery, and the recovery is hard. However, in people who are missing the meniscus and have pain, it can be very successful. Most people have less knee pain after this procedure.
After the surgery, you will probably wear a knee brace for the first 1 to 6 weeks. You also may need crutches for 1 to 6 weeks to prevent putting full weight on your knee. Most people can move the knee immediately after surgery to help prevent any stiffness. Pain is usually managed with medications.
Physical therapy may help you regain the motion and strength of your knee. Therapy lasts for between 4 and 6 months.
How soon you can return to work will depend on your job, but it can take anywhere from a few weeks to a few months. Most people have to wait between 6 months and 1 year to fully return to activities and sports.
Brockmeier SF, Rodeo SA. Knee: Meniscal injuries. In: DeLee JC, Drez D Jr, Miller MD, eds. DeLee and Drez's Orthopaedic Sports Medicine. 3rd ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 23, section B.
Miller RH III. Knee injuries. In: Canale ST, Beatty JH, eds. Campbell's Operative Orthopaedics. 11th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 43.
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and C. Benjamin Ma, MD, Assistant Professor, Chief, Sports Medicine and Shoulder Service, UCSF Dept of Orthopaedic Surgery. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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