Primary pulmonary hypertension
Pulmonary hypertension can result from narrowing of the small arteries (pulmonary arterioles) within the lung. The narrowing of the arteries creates resistance and an increased work load for the heart. The heart becomes enlarged and weakened from pumping blood against the resistance. Some symptoms include weakness, shortness of breath, fatigue, and fluid accumulation in the legs and abdomen. The goal of treatment is control of the symptoms, although the disease may develop into heart failure.
Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital.
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