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    Fibrinogen

    Serum fibrinogen; Plasma fibrinogen; Factor I; Hypofibrinogenemia test

    Fibrinogen is a protein produced by the liver. This protein helps stop bleeding by helping blood clots to form. A blood test can be done to tell how much fibrinogen you have in the blood.

    A sample of blood will be taken from your vein.

    There are no special steps you need to prepare for this test.

    You might feel slight pain or a sting when the needle is inserted to draw blood. You may feel throbbing afterward.

    Your doctor may order this test if you have problems with blood clotting such as excessive bleeding.

    The normal range is 200 - 400 milligrams per deciliter (mg/dL).

    Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

    The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.

    Abnormal results may be due to:

    • Excessive fibrinogen use (as in disseminated intravascular coagulation, DIC)
    • Fibrinogen deficiency (from birth, or acquired after birth)
    • Fibrinolysis
    • Hemorrhage

    The test may also be performed for placenta abruption.

    Risks

    There is very little risk involved with having your blood taken. Veins and arteries vary in size so it may be harder to get a blood sample from one person than another.

    Other risks slight risks from having blood drawn may include:

    • Excessive bleeding
    • Fainting or feeling light-headed
    • Hematoma (blood accumulating under the skin)
    • Infection (a slight risk any time the skin is broken)

    Note: This test is most often performed on people who have bleeding disorders. The risk of excessive bleeding is slightly greater in such people than for those who do not have bleeding problems.

    References

    Gailani D, Neff AT. Rare coagulation factor deficiencies. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa: Saunders Elsevier; 2012:chap 139.

    Ravi MV. Hemorrhagic disorders: Coagulation factor deficiencies In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 177.

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          Tests for Fibrinogen

          Review Date: 3/3/2013

          Reviewed By: Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.

          The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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          St. Luke's Hospital - 232 South Woods Mill Road - Chesterfield, MO 63017 Main Number: 314-434-1500 Emergency Dept: 314-205-6990 Patient Billing: 888-924-9200
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