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    Urinalysis

    Urine appearance and color; Routine urine test

    Urinalysis is the physical, chemical, and microscopic examination of urine. It involves a number of tests to detect and measure various compounds that pass through the urine.

    How the Test is Performed

    A urine sample is needed. Your health care provider will tell you what type of urine sample is needed. Two common methods of collecting urine are 24-hour urine collectionand clean catch urine specimen.

    The sample is sent to a lab, where it is examined for the following:

    Physical color and appearance:

    • What does the urine look like to the naked eye?
    • Is it clear or cloudy?
    • Is it pale or dark yellow or another color?

    The urine specific gravity test reveals how concentrated or dilute the urine is.

    Microscopic appearance:

    • The urine sample is examined under a microscope to look at cells, urine crystals, mucus, and other substances in the sample, and to identify any bacteria or other germs that might be present.

    Chemical appearance (urine chemistry):

    • A special stick (dipstick) tests for various substances in the urine. The stick contains little pads of chemicals that change color when they come in contact with the substances of interest.

    How to Prepare for the Test

    Certain medicines change the color of urine, but this is not a sign of disease. Yourhealth care providermay tell you to stop taking any medicines that can affect test results.

    Medicines that can change your urine color include:

    • Chloroquine
    • Iron supplements
    • Levodopa
    • Nitrofurantoin
    • Phenazopyridine
    • Phenothiazines
    • Phenytoin
    • Riboflavin
    • Triamterene

    How the Test Will Feel

    The test involves only normal urination, and there is no discomfort.

    Why the Test is Performed

    A urinalysis may be done:

    • As part of a routine medical exam to screen for early signs of disease
    • If you have signs of diabetes or kidney disease, or to monitor you if you are being treated for these conditions
    • To check for blood in the urine
    • To diagnose a urinary tract infection

    Additional conditions under which the test may be performed:

    • Acute bilateral obstructive uropathy
    • Acute nephritic syndrome
    • Acute tubular necrosis
    • Acute unilateral obstructive uropathy
    • Alkalosis
    • Alport syndrome
    • Analgesic nephropathy
    • Anorexia nervosa
    • Atheroembolic renal disease
    • Atrial myxoma
    • Bladder stones
    • Chronic bilateral obstructive uropathy
    • Chronic glomerulonephritis
    • Chronic or recurrent urinary tract infection
    • Chronic renal failure
    • Chronic unilateral obstructive uropathy
    • Chronic urethritis
    • Complicated UTI (pyelonephritis)
    • Congenital nephrotic syndrome
    • Cystinuria
    • Delirium
    • Dementia
    • Dementia due to metabolic causes
    • Diabetes insipidus -- central
    • Diabetic nephropathy/sclerosis
    • Enuresis
    • Epididymitis
    • Failure to thrive
    • Focal segmental glomerulosclerosis
    • Goodpasture syndrome
    • Heart failure
    • Hemolytic-uremic syndrome (HUS)
    • Henoch-Schonlein purpura
    • Insulin-dependent diabetes (IDD)
    • IgA nephropathy (Berger disease)
    • Injury of the kidney and ureter
    • Interstitial nephritis
    • Irritable bladder
    • Left-sided heart failure
    • Lupus nephritis
    • Malignant hypertension (arteriolar nephrosclerosis)
    • Medullary cystic kidney disease
    • Membranoproliferative GN I
    • Membranoproliferative GN II
    • Membranous nephropathy
    • Myelomeningocele (children)
    • Necrotizing vasculitis
    • Nephrotic syndrome
    • Noninsulin-dependent diabetes (NIDD)
    • Orchitis
    • Ovarian cancer
    • Paroxysmal nocturnal hemoglobinuria (PNH)
    • Polycystic kidney disease
    • Post-streptococcal GN
    • Prerenal azotemia
    • Primary amyloidosis
    • Prostate cancer
    • Prostatitis, acute
    • Prostatitis, chronic
    • Prostatitis, nonbacterial
    • Pyelonephritis, acute
    • Rapidly progressive (crescentic) glomerulonephritis
    • Reflux nephropathy
    • Renal papillary necrosis
    • Renal tubular acidosis, distal
    • Renal tubular acidosis, proximal
    • Renal vein thrombosis
    • Retrograde ejaculation
    • Rhabdomyolysis
    • Right-sided heart failure
    • Secondary systemic amyloidosis
    • Stress incontinence
    • Systemic lupus erythematosus
    • Systemic sclerosis (scleroderma)
    • Thrombotic thrombocytopenic purpura
    • Traumatic injury of the bladder and urethra
    • Ureterocele
    • Urethral stricture
    • Urethritis
    • Wegener granulomatosis
    • Wilms tumor

    Normal Results

    Normal urine may vary in color from almost colorless to dark yellow. Some foods (like beets and blackberries) may turn the urine a red color.

    Usually, glucose, ketones, protein, and bilirubin are not detectable in urine. The following are not normally found in urine:

    • Hemoglobin
    • Nitrites
    • Red blood cells
    • White blood cells

    Normal value ranges may vary slightly among different laboratories. Talk to yourhealth care providerabout the meaning of your specific test results.

    What Abnormal Results Mean

    Abnormal results may mean you have an illness. Your health care provider will discuss the results with you.

    Risks

    There are no risks.

    Considerations

    If a home test is used, the person reading the results must be able totell the differencebetween different colors, since the results are interpreted using a color chart.

    References

    McPherson RA, Ben-Ezra J. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. Philadelphia, PA:Elsevier Saunders; 2011:chap 28.

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    • Female urinary tract

      illustration

    • Male urinary tract

      illustration

      • Female urinary tract

        illustration

      • Male urinary tract

        illustration

      A Closer Look

        Tests for Urinalysis

        Review Date: 1/22/2013

        Reviewed By: Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.

        The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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