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Hepatitis A

Viral hepatitis; Infectious hepatitis

 

Hepatitis A is inflammation (irritation and swelling) of the liver from the hepatitis A virus.

Causes

 

The hepatitis A virus is found mostly in the stool and blood of an infected person. The virus is present about 15 to 45 days before symptoms occur and during the first week of illness.

You can catch hepatitis A if:

  • You eat or drink food or water that has been contaminated by stools (feces) containing the hepatitis A virus. Unpeeled and uncooked fruits and vegetables, shellfish, ice, and water are common sources of the disease.
  • You come in contact with the stool or blood of a person who currently has the disease.
  • A person with hepatitis A passes the virus to an object or food due to poor hand-washing after using the toilet.
  • You take part in sexual practices that involve oral-anal contact.

Not everyone has symptoms with hepatitis A infection. Therefore, many more people are infected than are diagnosed or reported.

Risk factors include:

  • Overseas travel, especially to Asia, South or Central America, Africa and the Middle East 
  • IV drug use
  • Living in a nursing home center
  • Working in a health care, food, or sewage industry

Other common hepatitis virus infections include hepatitis B and hepatitis C. Hepatitis A is the least serious and mildest of these diseases.

 

Symptoms

 

Symptoms most often show up 2 to 6 weeks after being exposed to the hepatitis A virus. They are most often mild, but may last for up to several months, especially in adults.

Symptoms include:

  • Dark urine
  • Fatigue
  • Itching
  • Loss of appetite
  • Low-grade fever
  • Nausea and vomiting
  • Pale or clay-colored stools
  • Yellow skin (jaundice)

 

Exams and Tests

 

The health care provider will perform a physical exam, which may show that your liver is enlarged and tender.

Blood tests may show:

  • Raised IgM and IgG antibodies to hepatitis A (IgM is usually positive before IgG)
  • Elevated liver enzymes (liver function tests), especially transaminase enzyme levels

 

Treatment

 

There is no specific treatment for hepatitis A.

  • You should rest and stay well hydrated when the symptoms are the worst.
  • People with acute hepatitis should avoid alcohol and drugs that are toxic to the liver, including acetaminophen (Tylenol) during the acute illness and for several months after recovery.
  • Fatty foods may cause vomiting and are best avoided during the acute phase of the illness.

 

Outlook (Prognosis)

 

The virus does not remain in the body after the infection is gone.

Most people with hepatitis A recover within 3 months. Nearly all people get better within 6 months. There is no lasting damage once you've recovered. Also, you can't get the disease again. There is a low risk of death. The risk is higher among older adults and people with long-term liver disease. 

 

When to Contact a Medical Professional

 

Call your provider if you have symptoms of hepatitis.

 

Prevention

 

The following tips can help reduce your risk of spreading or catching the virus:

  • Always wash your hands well after using the restroom, and when you come in contact with an infected person's blood, stools, or other bodily fluid.
  • Avoid unclean food and water.

The virus may spread more rapidly through day care centers and other places where people are in close contact. Thorough hand washing before and after each diaper change, before serving food, and after using the toilet may help prevent such outbreaks.

Ask your provider about getting either immune globulin or the hepatitis A vaccine if you are exposed to the disease and have not had hepatitis A or the hepatitis A vaccine.

Common reasons for getting one or both of these treatments include:

  • You have hepatitis B or C or any form of long-term liver disease.
  • You live with someone who has hepatitis A.
  • You recently had sexual contact with someone who has hepatitis A.
  • You recently shared illegal drugs, either injected or noninjected, with someone who has hepatitis A.
  • You have had close personal contact over a period of time with someone who has hepatitis A.
  • You have eaten in a restaurant where food or food handlers were found to be infected or contaminated with hepatitis.
  • You are planning travel to where hepatitis A is common.

Vaccines that protect against hepatitis A infection are available. The vaccine begins to protect 4 weeks after you get the first dose. You will need to get a booster shot 6 to 12 months later for long-term protection.

Travelers should take the following steps to protect against getting the disease:

  • Avoid dairy products.
  • Avoid raw or undercooked meat and fish.
  • Beware of sliced fruit that may have been washed in unclean water. Travelers should peel all fresh fruits and vegetables themselves.
  • DO NOT buy food from street vendors.
  • Get vaccinated against hepatitis A (and possibly hepatitis B) if traveling to countries where outbreaks of the disease occur.
  • Use only carbonated bottled water for brushing teeth and drinking. (Remember that ice cubes can carry infection.)
  • If bottled water is not available, boiling water is the best way to get rid of hepatitis A. Bring the water to a full boil for at least 1 minute to make it safe to drink.
  • Heated food should be hot to the touch and eaten right away.

 

 

References

Kim DK, Bridges CB, Harriman KH; Advisory Committee on Immunization Practices (ACIP), ACIP Adult Immunization Work Group. Advisory Committee on immunization practices recommended immunization Schedule for adults aged 19 years or older--United States, 2016. MMWR Morb Mortal Wkly Rep. 2016;65(4):88-90. PMID: 26845417 www.ncbi.nlm.nih.gov/pubmed/26845417.

Pawlotsky J-M. Acute viral hepatitis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 148.

Robinson CL; Advisory Committee on Immunization Practices (ACIP), ACIP Child/Adolescent Immunization Work Group. Advisory Committee on Immunization Practices Recommended Immunization Schedules for Persons Aged 0 Through 18 Years--United States, 2016. MMWR Morb Mortal Wkly Rep. 2016;65(4):86-87. PMID: 26845283 www.ncbi.nlm.nih.gov/pubmed/26845283.

Sjogren MH, Bassett JT. Hepatitis A. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 78.

 
  • Hepatitis A

    Animation

  •  

    Hepatitis A - Animation

    If you have noticed lately you feel weak and itch, have a loss of appetite, dark urine, and a low-grade fever, you may be suffering from symptoms of hepatitis A. Hepatitis A is irritation and swelling of the liver from infection with the hepatitis A virus. The virus is usually found in the stools and blood of an infected person. You can catch hepatitis A if you eat or drink food or water contaminated by feces containing the virus. Fruits, vegetables, shellfish, ice, and water are common culprits. You can also catch the disease if you come into contact with the blood or stool of a person who has hepatitis A, when a person who has the disease and doesn't wash their hands after going to the bathroom touches other objects or food, or if you have sex that involves oral to anal contact. Risk factors also include international travel, especially to Asia or South or Central America, IV drug use, living in a nursing home, or working in a health care, food, or sewage industry. So, what do you do about hepatitis A? Symptoms will show up about two to six weeks after you are exposed to the virus. As stated, you may well have dark urine, feel weak, have itching, a loss of appetite, a low-grade fever, feel nauseous, and have yellowish skin. The symptoms are usually mild, but they may last for up to several months. Your doctor will perform a physical exam and may discover that you have an enlarged, tender liver. Blood tests can confirm you have hepatitis A. There is no specific treatment for hepatitis A. Your doctor will recommend that you rest when your symptoms are at their worst. You should also avoid alcohol and anything else that is toxic to the liver, such as acetaminophen, or Tylenol. Keep in mind that eating fatty foods may cause you to vomit, because your liver helps process fats from your body. The good news is the hepatitis A virus does not remain in your body after the infection has gone, but you do need to maintain good bathroom habits to keep from spreading the disease. Typically, you will recover in about three months, but some people do need six months to get better. If you have recently been exposed to hepatitis A and have not had hepatitis A before or have not received the hepatitis A vaccine series, ask your doctor or nurse about receiving either immune globulin or the hepatitis A vaccine.

  • Digestive system

    Digestive system - illustration

    The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.

    Digestive system

    illustration

  • Hepatitis A

    Hepatitis A - illustration

    A fly may act as a mechanical vector of diseases such as Hepatitis A, which means the fly carries the infective organism on its feet or mouth parts and contaminates food or water which a person then consumes. A biological vector actually develops an infective organism in its body and passes it along to its host, usually through its saliva. A fly can be a biological vector, as in the transmission of leishmaniasis by the sandfly.

    Hepatitis A

    illustration

  • Hepatitis A

    Animation

  •  

    Hepatitis A - Animation

    If you have noticed lately you feel weak and itch, have a loss of appetite, dark urine, and a low-grade fever, you may be suffering from symptoms of hepatitis A. Hepatitis A is irritation and swelling of the liver from infection with the hepatitis A virus. The virus is usually found in the stools and blood of an infected person. You can catch hepatitis A if you eat or drink food or water contaminated by feces containing the virus. Fruits, vegetables, shellfish, ice, and water are common culprits. You can also catch the disease if you come into contact with the blood or stool of a person who has hepatitis A, when a person who has the disease and doesn't wash their hands after going to the bathroom touches other objects or food, or if you have sex that involves oral to anal contact. Risk factors also include international travel, especially to Asia or South or Central America, IV drug use, living in a nursing home, or working in a health care, food, or sewage industry. So, what do you do about hepatitis A? Symptoms will show up about two to six weeks after you are exposed to the virus. As stated, you may well have dark urine, feel weak, have itching, a loss of appetite, a low-grade fever, feel nauseous, and have yellowish skin. The symptoms are usually mild, but they may last for up to several months. Your doctor will perform a physical exam and may discover that you have an enlarged, tender liver. Blood tests can confirm you have hepatitis A. There is no specific treatment for hepatitis A. Your doctor will recommend that you rest when your symptoms are at their worst. You should also avoid alcohol and anything else that is toxic to the liver, such as acetaminophen, or Tylenol. Keep in mind that eating fatty foods may cause you to vomit, because your liver helps process fats from your body. The good news is the hepatitis A virus does not remain in your body after the infection has gone, but you do need to maintain good bathroom habits to keep from spreading the disease. Typically, you will recover in about three months, but some people do need six months to get better. If you have recently been exposed to hepatitis A and have not had hepatitis A before or have not received the hepatitis A vaccine series, ask your doctor or nurse about receiving either immune globulin or the hepatitis A vaccine.

  • Digestive system

    Digestive system - illustration

    The esophagus, stomach, large and small intestine, aided by the liver, gallbladder and pancreas convert the nutritive components of food into energy and break down the non-nutritive components into waste to be excreted.

    Digestive system

    illustration

  • Hepatitis A

    Hepatitis A - illustration

    A fly may act as a mechanical vector of diseases such as Hepatitis A, which means the fly carries the infective organism on its feet or mouth parts and contaminates food or water which a person then consumes. A biological vector actually develops an infective organism in its body and passes it along to its host, usually through its saliva. A fly can be a biological vector, as in the transmission of leishmaniasis by the sandfly.

    Hepatitis A

    illustration

A Closer Look

 

    Talking to your MD

     

      Self Care

       

      Tests for Hepatitis A

       

       

      Review Date: 8/20/2016

      Reviewed By: Michael M. Phillips, MD, Clinical Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

      The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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