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Renal vein thrombosis

Blood clot in the renal vein; Occlusion - renal vein

 

Renal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney.

Causes

 

Renal vein thrombosis is an uncommon disorder. It may be caused by:

  • Abdominal aortic aneurysm
  • Hypercoaguable state: clotting disorders
  • Dehydration (mostly in infants)
  • Estrogen use
  • Nephrotic syndrome
  • Pregnancy
  • Scar formation with pressure on the renal vein
  • Trauma (to the back or abdomen)
  • Tumor

In adults, the most common cause is nephrotic syndrome. In infants, the most common cause is dehydration.

 

Symptoms

 

Symptoms may include:

  • Blood clot to the lung
  • Bloody urine
  • Decreased urine output
  • Flank pain or low back pain

 

Exams and Tests

 

An exam may not reveal the specific problem. However, it may indicate nephrotic syndrome or other causes of renal vein thrombosis.

Tests include:

  • Abdominal CT scan
  • Abdominal MRI
  • Abdominal ultrasound
  • Duplex Doppler exam of the renal veins
  • Urinalysis may show protein in the urine or red blood cells in the urine
  • X-ray of the kidney veins (venography)

 

Treatment

 

The treatment is focused on preventing new clot formations and reducing the risk of the clot traveling to other locations in the body (embolization).

You may get medicines that prevent blood clotting (anticoagulants). You may be told to rest in bed or cut down on activity for a short time.

If sudden kidney failure develops, you may need dialysis for a short period.

 

Outlook (Prognosis)

 

Renal vein thrombosis most often gets better over time without lasting damage to the kidneys.

 

Possible Complications

 

Complications may include:

  • Acute renal failure (especially if thrombosis occurs in a dehydrated child)
  • End stage renal disease
  • Blood clot moves to the lungs ( pulmonary embolism )
  • Formation of new blood clots

 

When to Contact a Medical Professional

 

Call your health care provider if you have symptoms of renal vein thrombosis.

If you have experienced renal vein thrombosis, call your provider if you have:

  • Decrease in urine output
  • Breathing problems
  • Other new symptoms

 

Prevention

 

In most cases, there is no specific way to prevent renal vein thrombosis. Keeping enough fluids in the body may help reduce risk.

Aspirin is sometimes used to prevent renal vein thrombosis in people who have had a kidney transplant. Blood thinners such as warfarin may be recommended for some people with chronic kidney disease.

 

 

References

DuBose TD Jr, Santos RM. Vascular disorders of the kidney In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 125.

Ruggenenti P, Cravede P, Remuzzi G. Microvascular and macrovascular diseases of the kidney. In: Taal MW, Chertow GM, Marsden PA, et al, eds. Brenner and Rector's The Kidney . 9th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 34.

 
  • Kidney anatomy - illustration

    The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and stimulating red blood cell production.

    Kidney anatomy

    illustration

  • Kidney - blood and urine flow - illustration

    This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow.

    Kidney - blood and urine flow

    illustration

    • Kidney anatomy - illustration

      The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and stimulating red blood cell production.

      Kidney anatomy

      illustration

    • Kidney - blood and urine flow - illustration

      This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow.

      Kidney - blood and urine flow

      illustration

    A Closer Look

     

      Talking to your MD

       

        Self Care

         

          Tests for Renal vein thrombosis

           

           

          Review Date: 5/19/2015

          Reviewed By: Charles Silberberg, DO, private practice specializing in nephrology, affiliated with New York Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

          The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

           
           
           

           

           

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