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    Hypervitaminosis D

    Vitamin D toxicity

    Hypervitaminosis D is a condition that occurs after takingvery highdoses of vitamin D.


    An excess of vitamin D causes abnormally high levels of calcium in the blood. Thiscan severely damage the bones, soft tissues, and kidneys over time. It is almost always caused by forms of vitamin D thatneed a doctor's prescription.


    • Constipation
    • Decreased appetite (anorexia)
    • Dehydration
    • Fatigue
    • Irritability
    • Muscle weakness
    • Vomiting

    Exams and Tests

    • Excess calcium in the blood (hypercalcemia)
    • Excess calcium in the urine (hypercalciuria)
    • Excessive thirst (polydipsia)
    • High blood pressure
    • Passing large amounts of urine (polyuria)

    Tests to confirm the diagnosis:

    • 1,25-dihydroxy vitamin D levels
    • 25-hydroxy vitamin D levels
    • Serum calcium
    • Serum phosphorus
    • X-ray of the bone


    Stop takingvitamin D. Talk to your health care provider. In severe cases, other treatment may be needed.

    Outlook (Prognosis)

    Recovery is expected.

    Possible Complications

    • Dehydration
    • Hypercalcemia
    • Kidney damage
    • Kidney stones

    When to Contact a Medical Professional

    Call your health care provider if:

    • You or your child shows symptoms of hypervitaminosis D and has been taking more vitamin D than the recommended daily allowance
    • You or your child shows symptoms and has been taking a prescription form of vitamin D


    To prevent this condition, pay careful attention to the correct vitamin D dose.


          Tests for Hypervitaminosis D

            Review Date: 12/11/2011

            Reviewed By: Nancy J. Rennert, MD, Chief of Endocrinology & Diabetes, Norwalk Hospital, Associate Clinical Professor of Medicine, Yale University School of Medicine, New Haven, CT. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

            The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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