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Necrosis

 

Necrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed.

When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.

 

References

Wallig MA, Janovitz EB. Morphologic manifestations of toxic cell injury. In: Haschek WM, Rousseaux CG, Wallig MA. Haschek and Rousseaux's Handbook of Toxicologic Pathology. 3rd ed. Waltham, MA: Academic Press, Elsevier; 2013:chap 4.

 
  • Meningococcemia on the calves

    Meningococcemia on the calves - illustration

    Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) may occur. The tissue in areas may die (become necrotic or gangrenous). If the person survives, the areas heal with scarring.

    Meningococcemia on the calves

    illustration

  • Meningococcemia on the leg

    Meningococcemia on the leg - illustration

    Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin (petechiae and purpura), and the tissue in these areas may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring. This picture demonstrates more hemorrhage and little tissue death.

    Meningococcemia on the leg

    illustration

  • Meningococcemia associated purpura

    Meningococcemia associated purpura - illustration

    Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) typically occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.

    Meningococcemia associated purpura

    illustration

  • Necrosis of the toes

    Necrosis of the toes - illustration

    Necrosis is death of a portion of tissue or an organ in the body. Tissue death occurs when there is not enough blood supplied to the area, whether from trauma, radiation, or chemicals. Once necrosis is confirmed, it is not reversible.

    Necrosis of the toes

    illustration

    • Meningococcemia on the calves

      Meningococcemia on the calves - illustration

      Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) may occur. The tissue in areas may die (become necrotic or gangrenous). If the person survives, the areas heal with scarring.

      Meningococcemia on the calves

      illustration

    • Meningococcemia on the leg

      Meningococcemia on the leg - illustration

      Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin (petechiae and purpura), and the tissue in these areas may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring. This picture demonstrates more hemorrhage and little tissue death.

      Meningococcemia on the leg

      illustration

    • Meningococcemia associated purpura

      Meningococcemia associated purpura - illustration

      Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) typically occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.

      Meningococcemia associated purpura

      illustration

    • Necrosis of the toes

      Necrosis of the toes - illustration

      Necrosis is death of a portion of tissue or an organ in the body. Tissue death occurs when there is not enough blood supplied to the area, whether from trauma, radiation, or chemicals. Once necrosis is confirmed, it is not reversible.

      Necrosis of the toes

      illustration

    Tests for Necrosis

     

       

      Review Date: 8/14/2015

      Reviewed By: Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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