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TSH test

Thyrotropin; Thyroid stimulating hormone; Hypothyroidism - TSH; Hyperthyroidism - TSH; Goiter - TSH

 

A TSH test measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

How the Test is Performed

 

A blood sample is needed. Other thyroid tests that may be done at the same time include:

  • T3 test (free or total)
  • T4 test (free or total)

 

How to Prepare for the Test

 

There is no preparation needed for this test. Ask your health care provider about any medicines you are taking that may affect the test results. DO NOT stop taking any medicines without first asking your provider.

Medicines you may need to stop for a short time include:

  • Amiodarone
  • Dopamine
  • Lithium
  • Potassium iodide
  • Prednisone or other glucocorticoid medicines

 

How the Test will Feel

 

When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.

 

Why the Test is Performed

 

Your provider will order this test if you have symptoms or signs of an overactive or underactive thyroid gland. It is also used to monitor treatment of these conditions.

Your provider may also check your TSH level if you are planning to get pregnant.

 

Normal Results

 

Normal values range from 0.4 to 4.0 milli-international units per liter (mIU/L).

  • TSH values can vary during the day. It is best to have the test early in the morning.
  • Experts do not fully agree on what the upper number should be. Opinions vary from 2.5 to 4.0 mIU/L.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

If you are being treated for a thyroid disorder, your TSH level will likely be kept between 0.5 and 4.0 mIU/L, except when:

  • A pituitary disorder is the cause of the thyroid problem. A low TSH may be expected.
  • Someone has been treated for thyroid cancer. A low TSH may be best to prevent the thyroid cancer from coming back.
  • A woman is pregnant. The normal range for TSH is different for women who are pregnant. Your provider may suggest that you take thyroid hormone, even if your TSH is in the normal range.

 

What Abnormal Results Mean

 

A higher-than-normal TSH level is most often due to an underactive thyroid gland ( hypothyroidism ). There are many causes of this problem.

A lower-than-normal level may be due to an overactive thyroid gland, which can be caused by:

  • Graves disease
  • Toxic nodular goiter or multinodular goiter
  • Too much iodine in the body (due to receiving iodine contrast used during imaging tests, such as CT scan)
  • Taking too much thyroid hormone medicine or prescribed natural or over-the-counter supplements that contain thyroid hormone

Use of certain medicines may also cause a lower-than-normal TSH level. These include glucocorticoids/steroids, dopamine, certain chemotherapy drugs, and opioid painkillers such as morphine.

 

Risks

 

Veins and arteries vary in size from one person to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling lightheaded
  • Hematoma (blood buildup under the skin)
  • Infection (a slight risk any time the skin is broken)

 

 

References

Salvatore D, Davies TF, Schlumberger MJ, Hay ID, Larsen PR. Thyroid physiology and diagnostic evaluation of patients with thyroid disorders. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Textbook of Endocrinology . 13th ed. Philadelphia, PA: Elsevier; 2016:chap 11.

Weiss RE, Refetoff S. Thyroid function testing. In: Jameson JL, De Groot LJ, eds. Endocrinology: Adult and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 78.

 
  • Endocrine glands - illustration

    Endocrine glands release hormones (chemical messengers) into the bloodstream to be transported to various organs and tissues throughout the body. For instance, the pancreas secretes insulin, which allows the body to regulate levels of sugar in the blood. The thyroid gets instructions from the pituitary to secrete hormones which determine the pace of chemical activity in the body (the more hormone in the bloodstream, the faster the chemical activity; the less hormone, the slower the activity).

    Endocrine glands

    illustration

  • Pituitary and TSH - illustration

    The pituitary secretes thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism.

    Pituitary and TSH

    illustration

    • Endocrine glands - illustration

      Endocrine glands release hormones (chemical messengers) into the bloodstream to be transported to various organs and tissues throughout the body. For instance, the pancreas secretes insulin, which allows the body to regulate levels of sugar in the blood. The thyroid gets instructions from the pituitary to secrete hormones which determine the pace of chemical activity in the body (the more hormone in the bloodstream, the faster the chemical activity; the less hormone, the slower the activity).

      Endocrine glands

      illustration

    • Pituitary and TSH - illustration

      The pituitary secretes thyroid stimulating hormone (TSH), which stimulates the thyroid gland to secrete hormones that affect body metabolism.

      Pituitary and TSH

      illustration

    A Closer Look

     

      Self Care

       

        Tests for TSH test

         

         

        Review Date: 2/3/2016

        Reviewed By: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Editorial update 07/20/2016.

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