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    Urinary incontinence - injectable implant

    Intrinsic sphincter deficiency repair; ISD repair; Injectable bulking agents for stress urinary incontinence

    Injectableimplants are injections of material into the urethra to help control urine leakage (urinary incontinence) caused by a weak urinary sphincter. The sphincter is a muscle that allows your body to hold the urine in the bladder. If your sphincter muscle stops working well you will have urine leakage.


    The material that is injected is permanent. Coaptite and Macroplastique are examples of two brands.

    The doctor injects material through a needle into the wall of your urethra. This isthe tube that carries urine from your bladder. Thematerial bulks up the urethral tissue,causing it to close up. Thisstops urine from leaking out of your bladder.

    The type of anesthesia (pain relief) you receivefor this procedure may be one of the following:

    • Local anesthesia (only the area being worked on will be numb)
    • Spinal anesthesia (you will be numb from the waist down)
    • General anesthesia (you will be asleep and not able to feel pain)

    After you are numb or asleep from anesthesia, the doctor puts a medical device called a cystoscope into your urethra. The cystoscope allows your doctor to see the area.

    Thenthe doctor passes a needle through the cystoscope into your urethra. Material is injected into the wall of the urethra or bladder neck through this needle. The doctor can also injectmaterial into the tissue next to the sphincter.

    Theimplant procedure isusually done in the hospital. Or it is done in your doctor's clinic. The procedure takes about 20- 40 minutes.

    Why the Procedure Is Performed

    Implants can help both men and women.

    Men who have urine leakage after prostate surgery may choose to have implants.

    Women who have urine leakage and want a simple procedure to control the problem may choose to have an implant procedure. These women may not want to have surgery that requires general anesthesia.


    Risksof this procedure are:

    • Damage to the urethra or bladder
    • Urine leakage may get worse
    • Pain where the injection was done
    • Allergic reaction to the material
    • Implant material moves (migrates) to another area of the body

    Before the Procedure

    Tell your doctor or nurse what medicines you are taking. This includesmedicines, supplements, or herbs you bought without a prescription.

    You may be asked to stop taking aspirin, ibuprofen (Advil, Motrin) warfarin (Coumadin), and any othermedicines that make it hard for your blood to clot.

    On the day of your procedure:

    • You may be asked not to drink or eat anything for 6- 12 hours before the procedure. This will depend on what type of anesthesia you will have.
    • Take the medicines your doctor told you to take with a small sip of water.
    • Your doctor or nurse will tell you when to arrive at the hospital or clinic. Be sure to arrive on time.

    After the Procedure

    Most people can go home soon after the procedure. It may take up to a month before the injection fully works.

    It may become harder to empty your bladder. You may need to use a catheter for a few days. This and any other urinaryproblems usually go away.

    Outlook (Prognosis)

    You may need 2 or 3 more injections to get good results. If the material migrates, you may need additional treatments in the future.

    Implants canhelp most men who have had transurethral resection of the prostate (TURP).Implants help about half of men who have had their prostate gland removed to treat prostate cancer.


    Appell RA, Dmochowski RR, Blaivas JM, Gormley EA, et al. Female Stress Urinary Incontinence Update Panel of the American Urological Association Education and Research, Inc, Whetter LE. Update of AUA Guideline on the surgical management of female stress urinary incontinence. J Urol. 2010;183:1906-1914.

    Herschorn S. Injection therapy for urinary incontinence. In: Wein AJ, Kavoussi LR, Novick AC, et al., eds. Campbell-Walsh Urology. 10th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 74.


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                  Review Date: 12/12/2012

                  Reviewed By: Louis S. Liou, MD, PhD, Chief of Urology, Cambridge Health Alliance, Visiting Assistant Professor of Surgery, Harvard Medical School. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.

                  The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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