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Possible Interactions with: Milk Thistle

Milk Thistle; Silybum marianum; St. Mary's Thistle

If you are currently being treated with any of the following medications, you should not use milk thistle without first talking to your healthcare provider.

  • Antipsychotics -- includes butyrophenones (such as haloperidol) and phenothiazines (such as chlorpromazine, fluphenazine, and promethazine)
  • Phenytoin -- a medication used for seizures
  • Halothane -- a medication used during general anesthesia

Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes:

  • Allergy drugs -- such as fexofenadine (Allegra)
  • Drugs for high cholesterol -- such as lovastatin (Mevacor, Altocor)
  • Anti-anxiety drugs -- including alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan)
  • Antiplatelet and anticoagulant drugs (blood thinners) -- including clopidogrel (Plavix) and warfarin (Coumadin)
  • Some cancer drugs
 

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          Review Date: 6/13/2007  

          Reviewed By: Steven D. Ehrlich, N.M.D., private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.

          The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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